Medications against drugs: Development of medications to prevent and treat substance use disorders

Authors

  • Ivan Dario Montoya National Institute on Drug Abuse (NIDA) of the United States.

DOI:

https://doi.org/10.7203/metode.12.18411

Keywords:

medications development, substance use disorders, treatment, clinical trials

Abstract

Substance use disorder (SUD) is a significant public health concern. Unfortunately, there are few safe and effective medications to treat SUD and efficacy is suboptimal. There are important financial and scientific obstacles to develop new compounds, but recent advances in the discovery of new brain receptors and neurocircuits are offering opportunities to develop new pharmacotherapies. A systematic scientific approach to develop medications is required to demonstrate their safety and efficacy, bring it to market, and prescribe it to patients. The purpose of this manuscript is to provide a general overview of the challenges and opportunities in medications development for SUD, describe the phased approach of this development, the medications approved, and those that appear most promising.

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Author Biography

Ivan Dario Montoya, National Institute on Drug Abuse (NIDA) of the United States.

Deputy Director of the Division of Therapeutics and Medical Consequences (DTMC) of the National Institute on Drug Abuse (NIDA) of the United States. He received a Doctor in Medicine and Surgery degree and completed specialization in Psychiatry at the University of Antioquia (Colombia). He was a Fulbright Fellowship and received a Master’s in Public Health from The Johns Hopkins University. He did a Post-Doctoral Fellowship at the Intramural Research Program of NIDA. He leads a large program of research that supports the research and development of pharmacological and non-pharmacological treatments for Substance Use Disorders. He has published extensively in the areas of etiology, prevention, treatment, and medical consequences of drug abuse.

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Published

2022-02-02

How to Cite

Montoya, I. D. (2022). Medications against drugs: Development of medications to prevent and treat substance use disorders. Metode Science Studies Journal, (12), 87–93. https://doi.org/10.7203/metode.12.18411
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Issue

The future of science (2022)

Section

Willpower hijacked. The science of addictions

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