New era in the fight against cancer: Evolution and cancer: Progress in tumour treatments
DOI:
https://doi.org/10.7203/metode.78.2469Keywords:
targeted therapies, anti-target drugs, tyrosine kinase inhibitors, resistance mechanisms, screening
Abstract
In recent decades, oncohematology has witnessed major advances in cancer treatment and survival. The toxicity associated with classical chemotherapy, and the need to improve the efficacy and tolerance to treatment, have led to a flood of research activity and many fruitful results. Much of this effort has been focused on developing «targeted therapies» directed against specific functional alterations, which are key to tumour cell survival. Thus, greater treatment efficacy is sought whilst the patient pays a lower cost in terms of toxicity. Advances in other fields of oncology and epidemiology, surgery and radiation therapy have also contributed to the constant advancement of oncology. In short, we glimpse a future ahead that is full of hope for cancer patients and, at the same time, exciting for physicians and researchers alike.
Downloads
Author Biographies
Ana Lluch Hernández, University Hospital Clinic, Valencia (Spain).
José Alejandro Pérez-Fidalgo, University Hospital Clinic, Valencia (Spain).
Paloma Martín Martorell, University Hospital Clinic, Valencia (Spain).
References
Arora, A. and E. M. Scholar, 2005. «Role of Tyrosine Kinase Inhibitors in Cancer Therapy». The Journal of Pharmacology and Experimental Therapeutics, 315: 971-979. DOI: <10.1124/jpet.105.084145>.
Berry, D. et al., 2005. «Effect of Screening and Adjuvant Therapy on Mortality from Breast Cancer». The New England Journal of Medicine, 353: 1784-1792. DOI: <10.1056/NEJMoa050518>.
Calvo, A., 2006. «Ehrlich y el concepto de “bala mágica”». Revista Española de Quimioterapia, 19: 90-92.
Fernández-Velilla Peña, M. et al., 2013. «Tratamiento de lesiones pulmonares mediante radioterapia estereotáxica extracraneal tras colocación guiada por tomografía computarizada de marcador Viscoil®: experiencia inicial». Radiología, 55(3): 225-232. DOI: <10.1016/j.rx.2011.09.020>.
Pass, H. et al., 2004. «Changes in Management Techniques and Patterns of Disease Recurrence over Time in Patients with Breast Carcinoma Treated with Breast-conserving Therapy at a Single Institution». Cancer, 101(4): 713-720. DOI: <10.1002/cncr.20410>.
Roth, B. J. et al., 2013. «Clinical Cancer Advances in 2012: Annual Report on Progress Against Cancer from the American Society of Clinical Oncology». Journal of Clinical Oncology, 31(1): 131-161. DOI: <10.1200/JCO.2012.47.1938>.
Downloads
Published
How to Cite
-
Abstract560
-
PDF152
-
PDF (Català)118
-
PDF (Español)201
Issue
Section
License
All the documents in the OJS platform are open access and property of their respective authors.
Authors publishing in the journal agree to the following terms:
- Authors keep the rights and guarantee Metode Science Studies Journal the right to be the first publication of the document, licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License that allows others to share the work with an acknowledgement of authorship and publication in the journal.
- Authors are allowed and encouraged to spread their work through electronic means using personal or institutional websites (institutional open archives, personal websites or professional and academic networks profiles) once the text has been published.
Similar Articles
Most read articles by the same author(s)
Make a Submission
Language
Information
Keywords
